Plant Transcription Factor Database
Previous version: v3.0
Daucus carota
AP2 Family
Species TF ID Description
DCAR_002494AP2 family protein
DCAR_005288AP2 family protein
DCAR_006477AP2 family protein
DCAR_007644AP2 family protein
DCAR_009289AP2 family protein
DCAR_010799AP2 family protein
DCAR_011157AP2 family protein
DCAR_012824AP2 family protein
DCAR_016319AP2 family protein
DCAR_017724AP2 family protein
DCAR_018848AP2 family protein
DCAR_019345AP2 family protein
DCAR_020067AP2 family protein
DCAR_020068AP2 family protein
DCAR_020759AP2 family protein
DCAR_023899AP2 family protein
DCAR_025537AP2 family protein
DCAR_025748AP2 family protein
DCAR_028264AP2 family protein
DCAR_031571AP2 family protein
DCAR_015264AP2 family protein
DCAR_019145AP2 family protein
DCAR_010874AP2 family protein
DCAR_017924AP2 family protein
DCAR_003445AP2 family protein
DCAR_002147AP2 family protein
DCAR_009065AP2 family protein
AP2 Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

Genes in the AP2 family have been shown to participate in the regulation of developmental processes, e.g. flower development, spikelet meristem determinacy, leaf epidermal cell identity, and embryo development.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444

Using an in vitro selection procedure, the DNA binding specificity of the two AP2 repeat containing protein ANT was found to be 5'-gCAC(A/G)N(A/T)TcCC(a/g)ANG(c/t)-3'. This consensus site is much longer than sites recognized by proteins containing a single AP2 repeat and neither AP2 repeat of ANT was alone capable of binding to the selected sequences, suggesting that both AP2 repeats make DNA contacts.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102